
Immunomodulatory response of vitamin D has long been known and recognised. The active form of vitamin D (1,25-dihydroxyvitamin D) has the potential role in normal human functioning of immunity. Many research analysis have played role in displaying the perspective of vitamin D and immunity.
It is a key mediator of innate immune function. Both macrophages respond to 25-hydroxyvitamin D (25D), whcich is a vitamin D metabolite,
It has been shown that there is a link between the normal functioning of the cells and the variations found in vitamin D status.
The T cells proliferation and with the over-arching effects being to suppress inflammation and promote antimicrobial responses .
Cholecalciferol , the active form of vitamin D is sent to many different areas of the body, which includes bones, intestines , lymphatic immune systems which have receptors to synthesise it. Coming to the immune system, T cells are known to accurately judge between invaders and self cells, thus preventing chances of having autoimmune disorders.
How to increase this fat soluble vitamin D intake? If your levels are below recommendations , then it is suggested to go for supplements. The dosage can be decided after discussing your diet and the amount of vitamin D3 supplementation needed. It is important to know that all fat soluble vitamins work synergistically together. It is important to have vitamin E and Vitamin A, through food sources or a multivitamin pill. Steadfast Medishield, which is an established company , provides supplementation of dosage of 60,000 IU Vitamin D 3 under the name Adferol. If you are supplementing with such dosage on your own, it is important to get your levels checked and take doctor’s advice on it.